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The Wonders of Ginger
Rhizome ginger (Zingiber officinale) has been used in Asia for centuries as a culinary spice and medicinally to treat various ailments. The mild young ginger root and the more pungent mature root are used to flavor Chinese and Japanese cuisine. During the Qing Dynasty, it was also used to make a ginger-flavored liquor called Canton. In Great Britain, ginger is used in the production of an invigorating drink called Crabbies Green Ginger Wine. Both Orientals and Arabs use ginger infusions to flavor their coffee and tea, while the West traditionally uses ginger in cookies and candies and beverages.
One of the most unusual uses of ginger was in pre-WWI British mounted regiments when a sprig of ginger root was placed in a horse’s anus during public ceremonies. A practice known as figging (or fousing) caused a burning sensation without causing permanent damage; It kept the horses on their heads and tails. You can well imagine that this practice in humans is observed within the S&M community.
Medicinally, ginger root (a misnomer as it is not a root but a horizontal underground stem) is used by TCM doctors for gastrointestinal ailments, nausea, vomiting, diarrhea and arthritis. In the United States it is used in folk medicine and alternative medicine to treat gastrointestinal upset, nausea, motion sickness, pregnancy-induced nausea and arthritis. It can report the positive results of recent scientific studies to gradually gain acceptance in traditional western medicine in this country.
The flavor and characteristic of ginger root is due to a mixture of zingerone, shogols and gingerol, a volatile oil that makes up about 3% of the dry weight of fresh ginger. Gingerol is a medicinal ingredient that has analgesic, sedative, antipyretic, antiemetic and antibacterial properties in addition to reducing gastrointestinal motility. ginger ( -gingerol) is a relative of capsaicin, the compound that gives peppers their hot spicy flavor. When gingerol is exposed to heat (such as during cooking) it turns into zingerone which has a more palatable less pungent and spicy-sweet aroma.
The mechanism of action of ginger is not well understood, although the antiemetic properties may be due to the inhibition of serotonin receptors which have direct effects on the gastrointestinal and central nervous system. The use of ginger in the treatment of osteoarthritis and rheumatism may be due to the fact that ginger inhibits the activation of tumor necrosis factor-alpha (TNF-a) and cyclooxygenase-2 (COX-2) expression, thus acting. As an anti-inflammatory agent.
Ginger has been used for years as an over-the-counter preparation to treat motion sickness without the sleep of drugs such as dimenhydrinate (Dramamine). It apparently works very well, according to some scientific studies conducted on Marine Corps cadets. Mythbusters explored a rather amusing “scientific” study on Discovery TV’s hit show [in “Episode 43: Seasickness – Kill or Cure” (premiered: Nov. 16, 2005 )] A number of non-pharmacological treatments, including placebo, have been used to combat Adam’s very sensitive motion sickness. Ginger has been one of the most successful “home remedies” to combat this disease in the program. Now back to the double-blind peer-reviewed published studies. Several trials in pregnancy-induced nausea show comparable efficacy to vitamin B6 and superiority of ginger over placebo in controlling morning sickness. A Cochrane review showed ginger to be a safe (for baby and mother) and effective antiemetic during pregnancy.
There are also studies to support the use of ginger in post-operative nausea (post anesthesia). However, ginger did not work well to control chemotherapy-induced nausea and vomiting.
How does ginger stack when treating arthritis pain? While many studies have shown mixed results when using ginger to treat osteoarthritis and rheumatoid arthritis, some trials have shown statistically significant pain relief and reduction in inflammation with the use of ginger. Ginger has also been studied in vitro models and animals for treating conditions such as bacterial and fungal infections, cancer and as an anti-hypertensive agent. However, many have not been successfully studied in humans.
Ginger does not appear to have any significant toxicity. Although the FDA considers ginger to be safe, there is a theoretical risk when using it with the blood thinner warfarin (Coumadin). High doses of ginger may increase protein time (PT) in those taking this drug. The only other caution that should be used with this herb is in people with gallbladder disease; As ginger releases bile from the gallbladder, the condition of people suffering from gallstones worsens.
Clinical trials typically use 250 mg to 1000 mg of standardized powdered ginger root in capsule form. This dose is taken one to four times a day. A successful regimen for pregnancy-induced nausea studies has been 250 mg four times daily.
In my neck of the woods, a simple drink that people consume today began as a local medicine. The “world famous” Blenheim Ginger Ale is bottled less than 15 miles from my home in Bennettsville, SC. Blenheim Ginger Ale is named after a natural mineral spring in Blenheim, SC. Dr. Cr May advised patients in the late 1800s to drink this mineral water to soothe their upset stomachs. When it was reported that the treatment worked, but many patients disliked the strong mineral taste of the water, he added Jamaican ginger to the water, thus creating the now famous ginger ale. Jamaican ginger has historically been used as a medicine. It is classified as a stimulant and carminative for treating dyspepsia and colic and a tea made from the root was a folk remedy for colds. In 1903 Dr. May worked with a partner to bottle the product under the Blenheim Bottling Company. To this day it is considered to be the oldest and smallest bottling company in America. Today, some people use “hot” red-topped Blenheim ginger ale medicinally, rather than a soft drink, to treat sore throats, colds, flu and their stomach aches. Renowned journalist Charles Kuralt featured ginger ale in one of his episodes of his famous “On the Road” TV series, and Penn Gillette (of the comic-magic duo Penn & Taylor) is reportedly a big fan of the drink. Penn was featured on the September 1994 cover of Wired magazine wearing a Blenheim T-shirt, bottle in hand. Hail!
Seto, B., “Ginger: An Overview”, AmFmPractice, June, 2007, Vol. 75, no. 11, aafp dot org/afp/20070601/1689.html
Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against seasickness. A controlled test in the open sea. Acta Otolaryngol 1988; 105:45-9.
Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991; 42:111–20.
Borrelli F, Capasso R, Aviello G, Pittler MH, Izzo AA. Efficacy and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005; 105:849–56.
Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000; 84:367–71.
Oltman RD, Marcussen KC. Effect of ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001; 44:2531–8.
Jiang X, Williams KM, Liauw WS, Ammit AJ, Roufogalis BD, Duke CC, et al. Effects of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005; 59:425–32.
Blenheim Shrine, Blenheimshrine
Aliverti, Brent, Blenheim Ginger Ale, theacf dot com/blenheim
Susan Jakes, “Beverages of Champions. Part One: Hot Coke with Ginger, a Possible Magic Elixir”
MythBusters Episode 43: Seasickness – Kill or Cure, dsc.discovery dot com/fansites/mythbusters/episode/00to49/episode_02.html
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